Tuberculosis (TB) vaccines are vaccinations intended for the prevention of tuberculosis. Immunotherapy as a defence against
Today, the only effective tuberculosis vaccine in common use is bacilli Calmette-Guérin (BCG), first used on humans in 1921
About three out of every 10,000 people who get the vaccine experience side effects, which are usually minor except in severely immuno-depressed individuals.
While BCG immunization provides fairly effective protection for infants and young children,(including defence against TB meningitis and miliary TB) its efficacy in adults is variable,ranging from 0% to 80%.
Several variables have been considered as responsible for the varying outcomes.
Demand for TB immunotherapy advancement exists because the disease has become increasingly drug-resistant.